DOESciDAC ReviewOffice of Science


ISSN: 1935-0570
Cover story: Interview with Dr. Robert Rosner, p9

Cover image
Penetration to the cell membrane of alpha-synuclein pentamer (green surface). It is thought that this process causes creation of pores in the membrane, leading to Parkinson's disease. Visualization courtesy of Igor Tsigelny, University of California-San Diego.
CONTENTS
ISSUE 9 FALL 2008
4
9
INTERVIEW: DR. ROBERT ROSNER COVER STORY
Approching Exascale
Dr. Robert Rosner, director of Argonne National Laboratory, discusses exascale computing, partnerships with industry, energy efficiency in HPC, and getting people excited about science.  
12
NUCLEAR ENERGY  
Advanced Simulation for Fast Reactor Analysis
Key to realizing the benefits of fast reactors is high-performance computing. Using advanced simulation techniques on petascale computers, scientists and engineers are addressing nuclear engineering problems that previously could be addressed only by experiment, or not at all.
22
MOLECULAR BIOLOGY
Simulation Provides Key to the Mystery of Molecular Machines
Using the power of leadership-class computers, researchers are gaining new insights into the mechanisms of voltage-gated ion channels.
28
PROJECT FOCUS: OPEN SCIENCE GRID
A National High-Throughput Facility for Science
The Open Science Grid strives to help satisfy the ever-growing computing and data management requirements of scientific researchers, especially collaborative science requiring high-throughput computing.
36
HARDWARE
Cray XMT Brings New Energy to High-Performance Computing
The Cray XMT holds the potential to substantially accelerate data analysis and predictive analytics for many complex challenges in energy, national security, and fundamental science that traditional computing cannot do.
42
GEOPHYSICAL SIMULATIONS
Computational Predictions of Earthquake Ground Motions and the Response of Major Structures
Realistically simulating ground motions, and the response of complex structures and systems, using high-performance computing can help investigators improve seismic safety and the integrity of critical structures, such as bridges and nuclear power plants.
54
EDITORIAL: IN MEMORIAM
Final Farewell to Dr. Ed Oliver
Dr. Thomas Zacharia of the SciDAC Review Editorial Board remembers Ed Oliver.
56
BACK COVER
The National Center for Computational Sciences (NCCS) delivers groundbreaking new science.