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| News |
| Medicine |
Cardiac Arrhythmia Mechanisms |
| In work funded by the National Institutes of Health, Gene Network Sciences researchers are using INCITE allocations on the Argonne Leadership Computing Facility's Blue Gene/P to rapidly test hypotheses for the initiation and maintenance of cardiac rhythm disorders. |
These large-scale computer simulations represent a promising tool to help identify the underlying electrical mechanisms for dangerous arrhythmias and determine the effects of interventions, such as drugs, that may prevent or exacerbate these arrhythmias. Certain activation sequences have proven to be particularly effective at inducing arrhythmias in canine experimental models. The researchers plan to study these sequences in large-scale simulations of the canine heart to identify the mechanism by which wave break and the induction of an arrhythmia might occur.
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